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GLP 1 Semaglutide

GLP-1 medications, like Semaglutide and Tirzepatide, are prescription drugs that help control blood sugar and can also promote weight loss. On average, users can lose significant weight, especially when combined with lifestyle changes.

It’s important to note that GLP-1 medications are not recommended for individuals with a history of certain thyroid cancers or pancreatitis, as studies have shown potential risks in these cases.

References: https://www.mayoclinic.org/diseases-conditions/type-2-diabetes/expert-answers/byetta/faq-20057955

Deciding whether Semaglutide or Tirzepatide is best for you depends on various factors, including your medical history, specific health conditions, goals, and how each medication works. Both Semaglutide and Tirzepatide are GLP-1 receptor agonists, but they have some differences that may influence your choice:

1. Mechanism of Action:

• Semaglutide: It is a GLP-1 receptor agonist that mimics the hormone GLP-1, helping to regulate blood sugar, reduce appetite, and promote weight loss.
• Tirzepatide: It is a dual GLP-1 and GIP (Gastric Inhibitory Polypeptide) receptor agonist. In addition to working like Semaglutide, it also targets GIP, which may enhance insulin secretion and contribute to more robust effects on weight loss and glucose control.

2. Effectiveness:

• Weight Loss: Tirzepatide has been shown to be more effective in clinical trials for weight loss than Semaglutide, although both medications are effective for this purpose.

3. Side Effects:

• Common Side Effects: Common side effects include nausea, vomiting, and diarrhea, but these can often be managed by gradually increasing the dosage as prescribed. In rare cases, GLP-1 drugs can cause low blood sugar, especially if used with other medications that lower blood sugar, like insulin.
  Tirzepatide may cause more pronounced gastrointestinal discomfort in some patients, but individual experiences vary.

4. Cost:

• Although Tirzepatide tends to have patients lose more weight, it is also more expensive.

To ensure your safety and minimize side effects, it’s crucial to follow the exact dosage and instructions provided by your assigned GetTrim™ health provider. If you have any questions about how to take your medication, don’t hesitate to contact us for guidance via your patient portal or email at support@gettrim.com. Taking more or less than prescribed can lead to unintended and potentially harmful side effects.

Yes, you can check out our Injection Instructions video here on YouTube along with other educational material: https://www.youtube.com/watch?v=A6VLnpQCCM0

Both Semaglutide and Tirzepatide are weekly injections.

You can take GLP-1 medications at any time of day, regardless of meals. If your dose is prescribed weekly, be sure to take it on the same day each week.

Side effects may occur but our doctors will start you at a low dose and slowly work you up to a higher maintenance dose. This usually mitigates most of the common side effects. However, if side effects are too great, you can stop immediately, and the side effects should reduce or be completely gone in a few days to 1-2 weeks.

While Semaglutide and Tirzepatide do not directly increase energy in the traditional sense (like a stimulant would), it helps by regulating blood sugar, reducing body weight, and improving metabolic health, all of which can lead to more consistent and sustainable energy levels.

If you miss a dose, contact us before taking your next one via your portal or at hello@gettrim.com. We may need to adjust your dosage to help minimize any potential side effects.

Yes. Store your GLP-1 medications in the refrigerator between doses. These medications are sensitive to temperature and can lose effectiveness if not stored properly.


You should remain on your GLP-1 therapy until your weight loss goal is met. At that time, you should then discuss with your doctor if remaining on a maintenance dose would be beneficial or even trying a no-drug period would be warranted.

As with any appetite suppressant medication, your appetite and cravings can come back once you stop taking your medication. If ingested calories start to increase, you may begin to gain weight back unless mitigated by increased activity and exercise.

No, unfortunately we do not at the moment but are working on a GetTrim™ app to stay connected and provide a post care plan to each GetTrim™ member.

When switching to our care, please share your previous prescription and dosage with your assigned GetTrim™ medical professional during the intake process. If medically appropriate, they will adjust and coordinate your dosage accordingly.